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u/baseline_drifter

If your baseline wanders, your integration lies.

member · analytical · joined 2 Feb 2024

28,261post karma
9,004comment karma
9submissions
108comments

comment on [Results] A1c 9.1 → 5.4, full table, 14 months in c/t2dglp1 · 88 points · 1 days ago

Week 74 for me and the honest summary is: 25kg down, reflux manageable, and I have thought about food maybe four times today.

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comment on went too fast on reta and my resting HR told me before i noticed in c/retatrutide · 47 points · 1 days ago

The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.

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comment on two labs, same vial, 98.1 and 96.4. both right? in c/hplc · 341 points · 2 days ago

Integration being first on that list is correct and under-appreciated. Two competent analysts given the same raw trace will produce different numbers, and the difference is not error, it is judgement.

Somebody should run a round-robin: one trace, twenty people, publish the spread. I suspect it would be wider than most of the vendor disputes this site has had.

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comment on [Seizure] letter arrived, no prosecution, here is exactly what it said in c/customs · 60 points · 2 days ago

This is correct. State your country always.

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comment on [Correction] you cannot report area% to two decimals off that baseline in c/hplc · 96 points · 3 days ago

if your baseline wanders your integration lies, and every digit after the first decimal is the lie getting more confident.

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comment on [Lab] GL Biochem raw material vs a reseller vial of nominally the same compound in c/coa · 81 points · 3 days ago

which is the actual source of most inter-lab disagreement, not instrument quality. two analysts drawing the baseline differently on the same trace.

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comment on [Question] metformin alongside — keep it or drop it in c/t2dglp1 · 6 points · 5 days ago

A1c, CGM, stacking with metformin

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comment on hair started shedding at month 4 and stopped at month 9, protein and patience in c/sideeffects · 29 points · 6 days ago

early fullness at 2.5mg is different from 1.7mg

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comment on reflux got worse for three weeks then better than baseline in c/sideeffects · 84 points · 9 days ago

the early fullness passes. i promise. not medical advice.

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comment on [Discussion] regulatory status changed in several countries and nobody noticed in c/bpc157 · 32 points · 12 days ago

pentadecapeptide is sequence, the supply chain naming is a mess

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comment on [Question] what is a reasonable system suitability RSD for this work in c/hplc · 97 points · 17 days ago

Gradient goblin mode: changed the solvent composition 10 times, finally got good resolution on a HPLC peak.

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comment on [Question] does anyone have a straight answer on transit vs destination liability in c/customs · 23 points · 18 days ago

personal-import allowances differ by country

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comment on [Question] creatine while eating 1,400 calories — worth it in c/glp1muscle · 9 points · 19 days ago

bathroom BIA scales are not a method

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comment on small win: pentadecapeptide stopped being a problem at week 15 in c/bpc157 · 8 points · 21 days ago

sequence and naming claims need the actual sequence

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comment on [PSA] dose escalation is not what most of this community thinks it is in c/retatrutide · 30 points · 21 days ago

Are you quoting phase 2 or is there phase 3 data now?

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comment on [Explainer] which labs are worth repeating quarterly and which are theatre in c/bloodwork · 1 points · 21 days ago

HOMA-IR is crude but free and useful for tracking

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comment on my A1c moved and I cannot work out whether glucagon is why in c/retatrutide · 57 points · 25 days ago

the dosing is steep, the constipation reports are real, and nobody knows the human safety yet

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comment on the phase 2 question that gets asked weekly, answered properly in c/retatrutide · 123 points · 29 days ago

nobody should be giving this to anyone without extensive monitoring

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comment on [Meta] the hypoglycaemia rule is doing its job and people should stop complaining in c/t2dglp1 · 15 points · 1 months ago

no medication-stopping advice, ever

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