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c/glp1women·submitted 1 months ago by u/mateusz_mensah

perimenopause — 8 things I got wrong before I got it right

Cautionbranch of 9 comments

Genuinely asking, not being difficult. Everyone in c/orforglipron repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 20 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is…

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9 comments, started 1 months ago
u/signe_villalobos108 points·1 months ago
it is in the wiki actually
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u/hair_shed_hannahMOD60 points·1 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/dose_creep_dan15 points·1 months ago

I am going to push back on this slightly.

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u/mateusz_mensahOP58 points·1 months ago

perimenopause and menopause weight physiology

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[removed]28 points·1 months ago

[removed by moderator]

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u/coa_forgery_watch30 points·1 months ago

Yeah, insulin resistance is under-researched.

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u/elodie_yilmaz7 points·1 months ago

Yeah, contraception is under-researched.

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u/niels_roos6 points·1 months ago

Yeah, contraception is under-researched.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/mateusz_mensahOP3 points·1 months ago

Yeah, insulin resistance is under-researched.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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