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c/glp1women·posted 4 months ago by u/bastian_eriksen

week 86 check-in — 26kg down, fatigue manageable, one thing confusing me

PCOS Slow Clap ×1

Trying to settle this properly because the thread from last year went in circles.

The claim: cycle matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 20 months without either producing anything.

What would actually settle it is 15 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

533 up / 99 down84% upvoted24 commentsid 2qgepo11 Mar 2026

24 comments

18 in this archive, depth 6

best — the order this archive was captured in

u/dose_creep_dan111 points·4 months ago

Sweden here. Waited 10 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/hair_shed_hannahMOD60 points·4 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/aleksi_grimaldi28 points·4 months ago·edited

Strongly agree. Cycle changes are documented.

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u/reads_the_wiki32 points·4 months ago

hair-loss on cycle is real

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u/emeka_chowdhury25 points·4 months ago

perimenopause and menopause weight physiology

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[deleted]11 points·4 months ago

[deleted]

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u/sanne_novak13 points·4 months ago

cycle changes are real and under-researched

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u/joaquin_trevino34 points·4 months ago

Respectfully this is a sample of one presented as a finding.

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u/greta_nilsen11 points·4 months ago

contraception interaction claims need citation

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u/georgi_haddad28 points·4 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/bastian_eriksenOP83 points·4 months ago

the trials mostly studied men, insulin resistance skipped

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u/blunt_coldbox_202432 points·4 months ago·edited

the trials mostly studied men, perimenopause skipped

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u/valeria_cardoso-10 points·4 months ago

no cycle-tracking data with identifying details

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u/ismael_chukwu1 point·4 months ago

I am going to push back on this slightly.

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u/santiago_villalobos37 points·4 months ago
i have this exact spreadsheet
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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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