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c/newbiequestions·posted 1 year ago by u/ms_fragmenter

what changed for me between week 20 and week 69

Discussion Slow Clap ×2 Sourced ×1 Clean Column ×3

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking beginner against eGFR for 11 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

6,823 up / 2,550 down73% upvoted49 commentsid 1qnmub6 Jan 2025

49 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/plain_titration371 points·1 year ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/gentle_correctionnice about it243 points·1 year ago

This is a good question, genuinely.

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u/dexa_twice_yearlybody comp87 points·1 year ago

Yeah, that is totally normal for week 5.

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u/britta_nakamura62 points·1 year ago

the basics question is not dumb

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u/yannick_salinas25 points·1 year ago

Yeah, that is totally normal for week 9.

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u/nordic_pricing309 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/britta_boateng114 points·1 year ago

This is a good question, genuinely.

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u/sanne_laurent186 points·1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/fabio_nkemelu41 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/elise_grimaldi13 points·1 year ago

what is a COA — certificate of analysis, document from the lab

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u/dario_bakken59 points·1 year ago

link the wiki instead of retyping, but politely

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u/ms_fragmenterOP34 points·1 year ago

no dose recommendations for individuals, even here

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u/constipation_clubside effects19 points·1 year ago

week two nothing happening — yes, that is normal

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u/arne_restrepo10 points·1 year ago

week two nothing happening — yes, that is normal

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/britt_abubakar124 points·1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/reads_the_wikiMOD75 points·1 year ago·edited

Removed a chain here. The rule is one line long and it is not negotiable.

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u/hugo_norgaard141 points·1 year ago

what is titration — it means going slow on the escalation

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u/nordic_pricing100 points·1 year ago

The basics question took me three weeks to understand. Wiki explained it eventually.

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u/nightowl_injector33 points·1 year ago

Are you on a pen or vial?

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u/nordic_pricing22 points·1 year ago

what is a COA — certificate of analysis, document from the lab

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u/denied_again_d49 points·1 year ago

week two nothing happening — yes, that is normal

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u/gentle_correctionnice about it40 points·1 year ago

rudeness is removed faster than bad questions

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u/britt_zamora84 points·1 year ago

Week 12 checking in: nothing on the scale, no nausea, wondering if the pen is broken. No, it is just week 12.

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u/greta_perrin0 points·1 year ago

Week 11 checking in: nothing on the scale, no nausea, wondering if the pen is broken. No, it is just week 11.

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[deleted]1 point·1 year ago

[deleted]

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u/aurel_mwangi1 point·1 year ago

Yeah, that is totally normal for week 14.

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u/sigrid_kaufmann1 point·1 year ago·edited

link the wiki instead of retyping, but politely

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u/rekha_vestergaard1 point·1 year ago

Strongly agree. No question is dumb here.

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The deliberately gentle community. Every question that gets an eye-roll elsewhere lives here: what does titration mean, why do I feel nothing in week two, is this normal, what is bac water, what is a COA. Rudeness is removed faster than bad questions.

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