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c/orforglipron·submitted 12 months ago by u/fasting_insulin_f

orforglipron vs oral GLP-1 — genuinely asking which matters more

Discussionbranch of 6 comments

Something I noticed reading old threads that I have not seen said out loud. The advice on ATTAIN in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the…

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6 comments, started 12 months ago
u/zeynep_ndiaye54 points·12 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/muscle_cramp_mo34 points·12 months ago

the absorption problem is solved by non-peptide structure

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u/chidi_yilmaz-28 points·12 months ago

the small molecule is whether this actually works long-term

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u/fasting_insulin_fOP29 points·12 months ago

ATTAIN and ACHIEVE are phase 12 trials

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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