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c/orforglipron·posted 1 year ago by u/canada_coverage

[Question] Sweden — has anyone got a straight answer on oral GLP-1

Question The Quiet One ×4 Sourced ×3

Week 19 update. 25kg down from the start, reflux basically gone since about week 59.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

1,500 up / 322 down82% upvoted47 commentsid 1uyiu328 Nov 2024

47 comments

13 in this archive, depth 3

best — the order this archive was captured in

u/search_before_post89 points·1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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[deleted]63 points·1 year ago

[deleted]

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u/trialwatch_theotrial nerd31 points·1 year ago

the small molecule is whether this actually works long-term

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u/neha_rahimi78 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/incretin_ivypharmacology18 points·1 year ago

the supply conversation changes if this approves

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u/erez_yilmaz59 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

Adding to this: non-peptide is doing more work than the comment implies.

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u/hamza_weiss0 points·1 year ago

Strongly agree. The supply impact would be huge.

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u/brigade_detector36 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/ahmed_okafor20 points·1 year ago

Strongly agree. The supply impact would be huge.

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u/enzo_ferrari14 points·1 year ago

Small correction: the trial was 13 weeks, not 29. Does not change your point but people will quote it.

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u/emeka_delgado16 points·1 year ago·edited

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/trialwatch_theotrial nerd6 points·1 year ago

availability speculation must be flaired Speculation

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u/graph_it_gary6 points·1 year ago·edited

Strongly agree.

Yes, exactly this, and it is the bit that took me 68 weeks to accept.

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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