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c/orforglipron·submitted 1 year ago by u/maren_sorensen

orforglipron vs ATTAIN — genuinely asking which matters more

Trial Databranch of 5 comments

ACHIEVE. That is the whole post, but I will justify it. Everything else people worry about in c/survodutide is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort ACHIEVE out first, and almost nobody does. I say this having got it wrong for 9 months. My eGFR…

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5 comments, started 1 year ago
u/discount_math_dm6 points·1 year ago

Crossposting this to c/survodutide because the people who need it are not reading this community.

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u/adaeze_cabrera8 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/reship_roulette2 points·1 year ago

Yeah, small molecule changes the whole game.

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u/fabio_lehtinen1 point·1 year ago

How many weeks between the two measurements?

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u/viktor_laurent1 point·1 year ago

the early fullness profile is speculative at this stage

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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