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c/orforglipron·posted 10 months ago by u/yannick_salinas

someone explain ACHIEVE to me like I have not read a paper in years

Paper Receipts ×5

Genuinely asking, not being difficult.

Everyone in c/darkspot repeats that non-peptide is important. I believe it, but I have never seen anyone show why, and when I search I get 18 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

2,267 up / 1,982 down53% upvoted6 commentsid xe3fra22 Sep 2025

6 comments

2 in this archive, depth 1

best — the order this archive was captured in

u/lina_bruun26 points·10 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/enzo_ferrari22 points·10 months ago·edited

Did anything else change in the same window?

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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