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c/reconstitution·posted 1 year ago by u/clara_weiss

[PSA] bacteriostatic water is not what most of this community thinks it is

PSA Clean Column ×8 Slow Clap ×1 Long Haul ×3

Quick one. Canada here.

dead space works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 18 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

26,854 up / 19,856 down57% upvoted52 commentsid 17zuvq12 Jul 2025

52 comments

28 in this archive, depth 4

best — the order this archive was captured in

u/nabila_espinoza690 points·1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/rasmus_mensah331 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/britta_nakamura-6 points·1 year ago

i am begging people to write down the concentration

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u/tl_dr_tina552 points·1 year ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/clara_weissOP383 points·1 year ago

Spent 4 weeks confused about concentration math until someone showed me the table. 15mg, 3mL, concentration is 15/3.

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u/clara_weissOP319 points·1 year ago

show your working or it is unhelpful

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u/santiago_ndiaye201 points·1 year ago

the concentration on the vial in marker is the most important step

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u/declared_value_dv371 points·1 year ago
this deserves more than 24 upvotes
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[removed]278 points·1 year ago

[removed by moderator]

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u/dexa_twice_yearlybody comp277 points·1 year ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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u/clara_weissOP163 points·1 year ago

Did you write the concentration on the vial?

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u/saskia_mwangi140 points·1 year ago
post the spreadsheet
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u/karim_ilunga113 points·1 year ago·edited

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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u/priya_guerrero28 points·1 year ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/elodie_grimaldi17 points·1 year ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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u/ahmed_rasmussen69 points·1 year ago

u-100 syringe, not u-40, or your math is off by factor of 2

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u/units_not_mgMOD50 points·1 year ago

Retitled to remove editorialising. Put the evidence in the body.

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u/ilias_steiner58 points·1 year ago

never post a calculation as advice without stating the concentration

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u/georgi_adebayo49 points·1 year ago

never post a calculation as advice without stating the concentration

Yes, exactly this, and it is the bit that took me 59 weeks to accept.

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u/a1c_arcT2D31 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/signe_grimaldi39 points·1 year ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/anjali_tamm14 points·1 year ago

Respectfully this is a sample of one presented as a finding.

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u/britta_nakamura8 points·1 year ago

dead space is real and the syringe matters

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u/sleep_apnea_sam7 points·1 year ago·edited

dead space is real and the syringe matters

Disagree on that part. 98.1% and 96.2% on the same vial is normal.

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u/erez_perrin4 points·1 year ago

never post a calculation as advice without stating the concentration

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u/runa_cabrera20 points·1 year ago

more water means more units for the same dose, which means finer resolution

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u/aleksi_lehtinen17 points·1 year ago

Show the arithmetic. Where did the units come from?

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u/marisol_frisk19 points·1 year ago

u-100 syringe, not u-40, or your math is off by factor of 15

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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