[Question] how do you actually verify reconstitution
Right, the reconstitution question again, but with numbers this time.
I have 13 data points over 14 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.
The thing I would flag for anyone new: the effect I am describing showed up at week 56, not week 10. People give up long before the interesting part.
Interested in whether this matches other people's logs or whether I am an outlier.
best — the order this archive was captured in
Two vials, two different concentrations, forgot which was which, almost made a 21 times error. Now I label everything.
What was the vial size and how much bac water?
bacteriostatic and sterile water are not interchangeable, do not use them that way
I am going to push back on this slightly.
This is the "correlation is mechanism" thing again. You changed three variables at once.
This is the "correlation is mechanism" thing again.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
bacteriostatic and sterile water are not interchangeable, do not use them that way
Not to be pedantic but concentration and bacteriostatic water are being used interchangeably and they are not interchangeable in real life.
genuine question, not being difficult: how do you know
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
bacteriostatic and sterile water are not interchangeable, do not use them that way
30mg vial, 2mL water, concentration is 30/2 — write it on the vial afterwards
dead space is real and the syringe matters
more water means more units for the same dose, which means finer resolution
never post a calculation as advice without stating the concentration
Did you write the concentration on the vial?
15mg vial, 2mL water, concentration is 15/2 — write it on the vial afterwards
i am begging people to write down the concentration
never post a calculation as advice without stating the concentration
I am going to push back on this slightly.
never post a calculation as advice without stating the concentration
Titration speed is a side-effect dial far more than an efficacy dial.
Mechanistically the bit that matters is units. It explains most of the early profile and a decent chunk of the outcome.
more water means more units for the same dose, which means finer resolution
more water means more units for the same dose, which means finer resolution
Adding to this: dead space is doing more work than the comment implies.
stopper coring on the 24th draw because you keep using the same entry point. rotate.
Yeah, showing the arithmetic is the fastest way for someone to spot the error.
Did you write the concentration on the vial?
dead space is real and the syringe matters
Spent 21 weeks confused about concentration math until someone showed me the table. 5mg, 2mL, concentration is 5/2.
- 1genuine question, not being difficult: how do you know11 comments in this branch · started by u/saskia_mwangi
- 2Did you write the concentration on the vial?6 comments in this branch · started by u/karim_ilunga