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c/reconstitution·submitted 3 months ago by u/saskia_rahimi

small win: units stopped being a problem at week 11

Explainerbranch of 6 comments

Been lurking in c/semaglutide for about 12 months and finally have something worth posting. Short version: week 44, 0.5mg, and dead space is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 9 threads, and the answers split roughly down the middle. What I actually want to…

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6 comments, started 3 months ago
u/runa_grimaldi607 points·3 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/julia_erdogan889 points·3 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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[removed]663 points·3 months ago

[removed by moderator]

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u/saskia_rahimiOP343 points·3 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/reflux_report247 points·3 months ago·edited

bacteriostatic and sterile water are not interchangeable, do not use them that way

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u/ilias_cabrera0 points·3 months ago

dead space is real and the syringe matters

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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