GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of [Explainer] why 1mL syringes cause overdoses and 0.3mL ones do not — 42 comments in the full submission. View in context.
1.4k
c/reconstitution·submitted 5 days ago by u/ilias_cabrera

[Explainer] why 1mL syringes cause overdoses and 0.3mL ones do not

Explainerbranch of 9 comments

Genuinely asking, not being difficult. Everyone in c/orforglipron repeats that dead space is important. I believe it, but I have never seen anyone show why, and when I search I get 17 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

Read the full submission and all 42 comments →

This branch

9 comments, started 4 days ago
u/britta_nakamura89 points·4 days ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

replysharereportpermalink
u/ilias_cabreraOP34 points·3 days ago

Reconstituted at 2mL when I meant 10mL. Caught it because the units looked wrong. Write the concentration.

replysharereportpermalink
u/sofia_danquah25 points·4 days ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

Disagree on that part. 97.9% and 97.6% on the same vial is normal.

replysharereportpermalink
u/hub_opssite staff13 points·3 days ago

That is net peptide content, not purity. Different number, different meaning.

replysharereportpermalink
u/emil_zamora31 points·4 days ago

20mg vial, 2mL water, concentration is 20/2 — write it on the vial afterwards

replysharereportpermalink
u/niels_roos10 points·4 days ago

u-100 syringe, not u-40, or your math is off by factor of 21

replysharereportpermalink
u/batch_number_bertievetting28 points·3 days ago

10mg vial, 2mL water, concentration is 10/2 — write it on the vial afterwards

replysharereportpermalink
u/soren_zamora24 points·3 days ago

30mg vial, 1mL water, concentration is 30/1 — write it on the vial afterwards

replysharereportpermalink
u/karim_ilunga19 points·3 days ago·edited

swirl, do not shake, or you are courting oxidation

replysharereportpermalink

← back to the whole thread

About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

88kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
More in c/reconstitution
c/reconstitution rules
  1. Show your numbers. "How many units?" with no mg and no mL cannot be answered.
  2. Never post a calculation as advice without stating the concentration it assumes.
  3. No sterile-compounding-for-others discussion. Personal handling only.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/bac_water_banditu/vial_math_verau/units_not_mgu/swirl_dont_shake
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →