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c/reconstitution·submitted 2 years ago by u/quarter_dose_queen

[Question] how do you actually verify concentration

Questionbranch of 5 comments

Been lurking in c/semaglutide for about 21 months and finally have something worth posting. Short version: week 51, 5mg, and mg/mL is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 35 threads, and the answers split roughly down the middle. What I actually want to know is…

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5 comments, started 2 years ago
u/hub_opssite staff817 points·2 years ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/vial_math_verasyringe math458 points·2 years ago

more water means more units for the same dose, which means finer resolution

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u/emil_okwuosa200 points·2 years ago

This is correct. 2mL versus 4mL is the common mistake.

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u/alcohol_aversion291 points·2 years ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/janek_ferrari241 points·2 years ago

Respectfully this is a sample of one presented as a finding.

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The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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