[Question] how do you actually verify concentration
Been lurking in c/semaglutide for about 21 months and finally have something worth posting.
Short version: week 51, 5mg, and mg/mL is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 35 threads, and the answers split roughly down the middle.
What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 45.
best — the order this archive was captured in
Titration speed is a side-effect dial far more than an efficacy dial.
more water means more units for the same dose, which means finer resolution
This is correct. 2mL versus 4mL is the common mistake.
dosing errors come from people reconstituting two vials differently and forgetting which is which
Respectfully this is a sample of one presented as a finding.
stopper coring on the 4th draw because you keep using the same entry point. rotate.
Is that 15mg vial or 5mg?
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Show the arithmetic. Where did the units come from?
bacteriostatic and sterile water are not interchangeable, do not use them that way
show your working or it is unhelpful
This is the "correlation is mechanism" thing again. You changed three variables at once.
Yeah, showing the arithmetic is the fastest way for someone to spot the error.
Is that 15mg vial or 31mg?
i am begging people to write down the concentration
Cosigning. The concentration on the vial in marker is load-bearing.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
The single most useful thing I did was write the concentration on the vial. Stopped all the confusion after that.
i am begging people to write down the concentration
Not convinced. The evidence does not support that reading.
This is correct. 2mL versus 2mL is the common mistake.
This is the "correlation is mechanism" thing again. You changed three variables at once.
dead space is real and the syringe matters
Show the arithmetic. Where did the units come from?
the concentration on the vial in marker is the most important step
the concentration on the vial in marker is the most important step
Disagree on that part. 99.3% and 93.7% on the same vial is normal.
swirl, do not shake, or you are courting oxidation
Dead space in the needle hub holds a small but non-trivial volume.
Yes, exactly this, and it is the bit that took me 65 weeks to accept.
15mg vial, 1mL water, concentration is 15/1 — write it on the vial afterwards
- 1Dead space in the needle hub holds a small but non-trivial volume. On…13 comments in this branch · started by u/alcohol_aversion
- 2Titration speed is a side-effect dial far more than an efficacy dial.5 comments in this branch · started by u/hub_ops