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Single comment threadYou are looking at one branch of week 46 check-in — 47kg down, the food-noise thing manageable, one thing confusing me — 32 comments in the full submission. View in context.
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c/retatrutide·submitted 2 years ago by u/burned_once_twice

week 46 check-in — 47kg down, the food-noise thing manageable, one thing confusing me

Cautionbranch of 5 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking retatrutide against ApoB for 29 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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5 comments, started 2 years ago
u/bilal_osei592 points·2 years ago

Not convinced. The evidence does not support that reading.

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u/burned_once_twiceOP384 points·2 years ago

triple agonism is dose escalation, do not generalise

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u/burned_once_twiceOP223 points·2 years ago

TRIUMPH phase 2 showed 98.6% weight loss but the early fullness profile on the highest arm was rough. Phase 2 != phase 3.

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u/emil_agyeman359 points·2 years ago

the 15mg arm is different from 12.5mg, results do not transfer

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u/jarno_cabrera519 points·2 years ago

the 15mg arm is different from 12.5mg, results do not transfer

Disagree on that part. 97.9% and 97.6% on the same vial is normal.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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