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c/retatrutide·posted 9 days ago by u/source_or_silence

reta made me not want food OR water and that is its own problem

Question

Confession thread, sort of.

I went from 10mg to 2.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 18 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have muscle cramps I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 18 reads it before doing the same thing.

241 up / 268 down47% upvoted10 commentsid 1mkuzz20 Jul 2026

10 comments

10 in this archive, depth 3

best — the order this archive was captured in

u/freya_baptista6 points·9 days ago

triple agonism is phase 2, do not generalise

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u/solene_ilunga4 points·9 days ago

I am going to push back on this slightly.

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u/signe_villalobos3 points·9 days ago

Are you quoting phase 2 or is there phase 3 data now?

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u/careful_gradient322 points·9 days ago

nobody should be giving this to anyone without extensive monitoring

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u/hassan_nilsen3 points·9 days ago

Are you quoting phase 2 or is there phase 3 data now?

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u/iman_castellanos4 points·9 days ago

the glucagon component changes the side effect profile, not just the efficacy

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u/source_or_silenceOP3 points·9 days ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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u/naomi_erdogan3 points·8 days ago·edited

retatrutide is not approved anywhere for human use, posts must not read as instructions

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
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