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crossposted from c/sideeffects by u/adaeze_brandt — help me understand nausea, I have read the wiki twice
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c/retatrutide·posted 1 year ago by u/honest_syringe_2025

does phase 2 actually matter or is it forum lore at this point

Trial Data Receipts ×4 Cold Box ×2 Slow Clap ×3

Trying to settle this properly because the thread from last year went in circles.

The claim: glucagon matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 20 months without either producing anything.

What would actually settle it is 9 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

8,872 up / 1,458 down86% upvoted24 commentsid 1t7zwd29 Jan 2025

24 comments

3 in this archive, depth 2

best — the order this archive was captured in

u/crosspost_bot_no0 points·1 year ago

This is correct. Triple agonism is genuinely different.

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u/incretin_ivyMOD330 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/honest_syringe_2025OP0 points·1 year ago

heart rate and dose escalation need actual measurements, not impressions

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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