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c/retatrutide·posted 1 year ago by u/matias_falk

[Lab] 6th independent test on QSC, and the trend is the interesting part

Lab Long Haul ×2 Sourced ×3 Well Actually ×1

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking retatrutide against ApoB for 3 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

30,756 up / 25,889 down54% upvoted20 commentsid a1z2g26 Jun 2025

20 comments

7 in this archive, depth 3

best — the order this archive was captured in

u/priya_weiss1.1k points·1 year ago

the glucagon component changes the side effect profile, not just the efficacy

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u/reta_and_regretMOD743 points·1 year ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/emil_wojcik243 points·1 year ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/employer_carveout63 points·1 year ago

research use only, handling and analysis, not protocols

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u/isabela_nilsen285 points·1 year ago

This is correct. Triple agonism is genuinely different.

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u/bilal_osei193 points·1 year ago

triple agonism is phase 2, do not generalise

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u/signe_villalobos444 points·1 year ago

triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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