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c/retatrutide·submitted 2 years ago by u/customs_seizure_sid

what changed for me between week 10 and week 59

Discussionbranch of 7 comments

Been lurking in c/progresspics for about 14 months and finally have something worth posting. Short version: week 15, 0.5mg, and TRIUMPH is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 37 threads, and the answers split roughly down the middle. What I actually want to know…

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7 comments, started 2 years ago
u/lina_bruun209 points·2 years ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/yannick_salinas125 points·2 years ago

Mechanistically the bit that matters is triple agonist. It explains most of the early profile and a decent chunk of the outcome.

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u/lane_watchermod · logistics50 points·2 years ago

This is correct. Triple agonism is genuinely different.

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u/yannick_barros39 points·2 years ago·edited

This is correct.

Yes, exactly this, and it is the bit that took me 81 weeks to accept.

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u/dead_space_doug55 points·2 years ago

That is net peptide content, not purity. Different number, different meaning.

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u/renzo_yildiz75 points·2 years ago

triple agonism is glucagon, do not generalise

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u/injection_site_iris46 points·2 years ago

Did you actually measure heart rate or is that a feeling?

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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