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c/retatrutide·submitted 2 years ago by u/naomi_erdogan

week 56 check-in — 46kg down, early fullness manageable, one thing confusing me

Cautionbranch of 11 comments

I have had 21 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 22 days on nominally the same lane, which matters more in summer than in February. The independent number came back 93.7% against a claimed…

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11 comments, started 2 years ago
u/careful_gradient_again362 points·2 years ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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u/yannick_barros178 points·2 years ago

triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual

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u/careful_gradient_again62 points·2 years ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/trialwatch_theotrial nerd119 points·2 years ago·edited

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/nordic_pricing39 points·2 years ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/jarno_cabrera531 points·2 years ago

Respectfully this is a sample of one presented as a finding.

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u/customs_seizure_sid106 points·2 years ago

The glucagon component does different things than dual agonism. The nausea are not just amplified versions.

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u/source_or_silence82 points·2 years ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/tired_ledger_notes43 points·2 years ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/niels_lindqvist34 points·2 years ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/vito_beaulieu16 points·2 years ago

Did you actually measure heart rate or is that a feeling?

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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