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c/retatrutide·submitted 2 years ago by u/sofia_wikstrom

anyone else notice phase 2 kicking in around week 30

Discussionbranch of 7 comments

Something I noticed reading old threads that I have not seen said out loud. The advice on TRIUMPH in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with…

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7 comments, started 2 years ago
u/incretin_ivypharmacology114 points·2 years ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/sofia_wikstromOP0 points·2 years ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/emil_agyeman1 point·2 years ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/sofia_wikstromOP1 point·2 years ago

This is correct. Triple agonism is genuinely different.

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u/deleted_my_history1 point·2 years ago

heart rate and dose escalation need actual measurements, not impressions

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u/hassan_nilsen1 point·2 years ago

the dosing is steep, the early fullness reports are real, and nobody knows the human safety yet

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u/quiet_moderatormod54 points·2 years ago

Which trial arm and what was the n?

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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