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c/retatrutide·submitted 3 months ago by u/tired_ledger_notes

[Lab] 17th independent test on QSC, and the trend is the interesting part

Labbranch of 8 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking retatrutide against eGFR for 11 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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8 comments, started 3 months ago
u/incretin_ivyMOD442 points·3 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/rohan_cardoso339 points·3 months ago

You have restated the marketing copy. What is the actual substance here.

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u/ewan_marchand111 points·3 months ago·edited

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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u/burned_once_twice88 points·3 months ago

This is correct. Triple agonism is genuinely different.

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u/divya_bakken61 points·3 months ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/titration_marshalmod · c/semaglutide73 points·3 months ago

This is correct.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/trialwatch_theotrial nerd77 points·3 months ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/crosspost_bot_no22 points·3 months ago

triple agonism is dose escalation, do not generalise

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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