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c/retatrutide·posted 3 months ago by u/trialwatch_theo

my ALT moved and I cannot work out whether phase 2 is why

Discussion Well Actually ×9 Long Haul ×1

Right, the triple agonist question again, but with numbers this time.

I have 13 data points over 36 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 52, not week 6. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

4,408 up / 3,222 down58% upvoted26 commentsid xabv0h14 Apr 2026

26 comments

8 in this archive, depth 4

best — the order this archive was captured in

u/titration_marshalmod · c/semaglutide126 points·3 months ago
reading this at 2am on my 66th week. thank you.
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[deleted]49 points·3 months ago

[deleted]

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u/blunt_coldbox_2024112 points·3 months ago

Did you actually measure heart rate or is that a feeling?

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u/reta_and_regretMOD72 points·3 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/trialwatch_theoOPtrial nerd55 points·3 months ago

This is correct. Triple agonism is genuinely different.

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u/employer_carveout80 points·3 months ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/yara_lindholm40 points·3 months ago

heart rate and dose escalation need actual measurements, not impressions

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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