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c/t2dglp1·posted 2 months ago by u/kasper_cabrera

what would you tell week-1 you about glycaemic control

CGM

Trying to settle this properly because the thread from last year went in circles.

The claim: CGM matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 11 months without either producing anything.

What would actually settle it is 23 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

254 up / 62 down80% upvoted17 commentsid 1vmp8912 May 2026

17 comments

14 in this archive, depth 5

best — the order this archive was captured in

u/marisol_moreau13 points·2 months ago

Strongly agree. A1c matters as much as weight.

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u/tomas_kimani3 points·2 months ago

Which country? Half the answers in this thread only apply in France.

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u/jonas_cardoso9 points·2 months ago

metformin combo is standard

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u/cloudy_vial_carol13 points·2 months ago

Crossposting this to c/tapering because the people who need it are not reading this community.

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u/rasmus_kimani4 points·2 months ago

I am going to push back on this slightly.

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u/step_count_stan7 points·2 months ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/britt_abubakar9 points·2 months ago·edited
^ this
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u/osman_ferrari2 points·2 months ago

Strongly agree. A1c matters as much as weight.

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u/tired_ledger_notes6 points·2 months ago

Half-life is about 168 hours, so steady state lands around week 22–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/hassan_ostergaard4 points·2 months ago

the weight-loss conversation drowns out glycaemic control sometimes

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[removed]3 points·2 months ago

[removed by moderator]

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u/joaquin_trevino2 points·2 months ago·edited

the 38 A1c trend is the answer

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u/tomas_kimani1 point·2 months ago

hypoglycaemia risk when stacked with metformin

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u/arne_nyberg1 point·2 months ago

Small correction: the trial was 20 weeks, not 5. Does not change your point but people will quote it.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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