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c/tapering·submitted 2 months ago by u/rafael_sjoberg

[Question] Sweden — has anyone got a straight answer on interval stretching

Questionbranch of 7 comments

Right, the tapering question again, but with numbers this time. I have 21 data points over 10 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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7 comments, started 2 months ago
u/zeynep_weiss64 points·2 months ago

This is correct. Discontinuation data is real.

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u/injection_site_iris17 points·2 months ago

This is correct.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/arne_restrepo50 points·2 months ago

STEP 1 and SURMOUNT-4 discontinuation arms show regain

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u/marta_weiss25 points·2 months ago

appetite return timelines vary interval stretching

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u/farid_kuipers27 points·2 months ago

Genuine question — what concentration were you at?

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u/rafael_sjobergOP19 points·2 months ago

the 16 week discontinuation arm is the data

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u/nikhil_lindqvist32 points·2 months ago

Yeah, regain is not a failure.

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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