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c/tapering·submitted 2 years ago by u/coldchain_karen

[Vendor] WXT order #7 — the Netherlands, 3 days, no drama, receipts inside

Regainbranch of 16 comments

Right, the discontinuation question again, but with numbers this time. I have 8 data points over 32 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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16 comments, started 2 years ago
u/helga_vermeulen56 points·2 years ago

tapering instructions are not welcome here

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u/coldchain_karenOPcold chain32 points·2 years ago

Stalled for 18 weeks, changed nothing, and it started moving again on week 66.

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u/peptidemeter_pat20 points·2 years ago

Disagree. What you are describing is consistent with discontinuation, not with what you concluded.

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u/quarter_dose_queenlow and slow15 points·2 years ago

cite the discontinuation data rather than guessing regain rates

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u/andres_restrepo17 points·2 years ago

Has anyone actually got this in writing, or is it forum lore at this point?

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u/priya_weiss15 points·2 years ago

the regain is treatment of chronic condition ending, not failure

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u/pavel_halvorsen3 points·2 years ago

interval stretching versus dose reduction

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u/rafael_sjoberg2 points·2 years ago

This is correct. Discontinuation data is real.

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u/arne_restrepo43 points·2 years ago

STEP 1 and SURMOUNT-4 discontinuation arms show regain

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u/taper_off_tabitha29 points·2 years ago

STEP 1 and SURMOUNT-4 discontinuation arms show regain

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/lift_heavy_thingsresistance training24 points·2 years ago

no shaming people who restart

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u/neha_mwangi36 points·2 years ago

coming off deliberately, not by accident

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u/TitrationTortoiseslow and boring27 points·2 years ago

coming off deliberately, not by accident

Adding to this: regain is doing more work than the comment implies.

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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