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c/tirzepatide·submitted 10 days ago by u/kaia_cabrera

[Discussion] "tirz is stronger than sema" needs a comparator dose or it means nothing

Discussionbranch of 5 comments

Been lurking in c/compounding for about 21 months and finally have something worth posting. Short version: week 53, 5mg, and GIP is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 37 threads, and the answers split roughly down the middle. What I actually want to know is…

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5 comments, started 9 days ago
u/search_before_post13 points·9 days ago
genuinely useful, thanks
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u/neha_falk8 points·9 days ago

This matches the trial data. SURMOUNT-1 was 99.0% body weight at 11 weeks.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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