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c/tirzepatide·submitted 5 months ago by u/thyroid_tangent

what changed for me between week 5 and week 48

Questionbranch of 7 comments

Confession thread, sort of. I went from 0.5mg to 12.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 16 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have early…

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7 comments, started 5 months ago
u/taper_off_tabitha31 points·5 months ago

stalled on sema, tried tirz, and the curves were actually different shapes

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u/dexa_twice_yearlyMOD18 points·5 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/ignacio_vanhecke17 points·5 months ago

Not convinced. The evidence does not support that reading.

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u/hugo_bergstrom13 points·5 months ago

stalled on sema, tried tirz, and the curves were actually different shapes

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u/kian_ekstrom6 points·5 months ago·edited

the muscle cramps from tirz is different, not necessarily worse

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u/blunt_coldbox293 points·5 months ago·edited

Respectfully this is a sample of one presented as a finding.

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u/hassan_nilsen4 points·5 months ago

You have restated the marketing copy. What is the actual substance here.

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Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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