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c/tirzepatide·submitted 7 months ago by u/emil_barros

switched from 7.5mg to 15mg and the nausea got better, not worse

Titrationbranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 2 months without either producing anything. What would actually settle it is 11 people measuring the same…

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6 comments, started 7 months ago
u/quiet_moderatormod39 points·7 months ago

How long at each step before you escalated?

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u/certified_referenceQC18 points·7 months ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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[removed]13 points·7 months ago

[removed by moderator]

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u/tarek_lokken11 points·7 months ago

Hard agree. The food noise disappears differently on the two compounds.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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