switched from 7.5mg to 15mg and the nausea got better, not worse
Trying to settle this properly because the thread from last year went in circles.
The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 2 months without either producing anything.
What would actually settle it is 11 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.
If you have data, post the data. If you have an opinion, flair it as an opinion.
best — the order this archive was captured in
do not crack the pen, we have been over this
do not crack the pen, we have been over this
Adding to this: Mounjaro is doing more work than the comment implies.
do not crack the pen, we have been over this
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
This matches the trial data. SURMOUNT-1 was 98.0% body weight at 5 weeks.
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
week 17 on Mounjaro and the appetite profile is genuinely different from sema
stalled on sema, tried tirz, and the curves were actually different shapes
Week 57 on Mounjaro and 45kg down. The appetite reduction feels different from sema in ways I do not have words for yet.
the 15mg is the top of the pen, not the required dose
stalled on sema, tried tirz, and the curves were actually different shapes
the fatigue from tirz is different, not necessarily worse
This matches the trial data. SURMOUNT-1 was 93.7% body weight at 9 weeks.
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
This is the "correlation is mechanism" thing again. You changed three variables at once.
SURMOUNT data is messier than STEP data but the weight loss is there
How long at each step before you escalated?
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Hard agree. The food noise disappears differently on the two compounds.
the appetite change on tirz is more than just reduced hunger, it is different machinery
the muscle cramps from tirz is different, not necessarily worse
- 1Did you stay on semaglutide or switch? The outcome is different if you are…8 comments in this branch · started by u/bastian_ekstrom
- 2How long at each step before you escalated?6 comments in this branch · started by u/quiet_moderator