anyone else notice SURMOUNT kicking in around week 30
Trying to settle this properly because the thread from last year went in circles.
The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 19 months without either producing anything.
What would actually settle it is 11 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.
If you have data, post the data. If you have an opinion, flair it as an opinion.
best — the order this archive was captured in
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
Week 42 on Mounjaro and 40kg down. The appetite reduction feels different from sema in ways I do not have words for yet.
Switched from sema at 0.25mg to tirz at 15mg. Different drugs, cannot compare the doses directly.
Not convinced. The evidence does not support that reading.
do not crack the pen, we have been over this
This is the "correlation is mechanism" thing again. You changed three variables at once.
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
You have restated the marketing copy. What is the actual substance here.
the reflux from tirz is different, not necessarily worse
This matches the trial data. SURMOUNT-1 was 97.9% body weight at 4 weeks.
Zepbound and Mounjaro are literally the same drug, the name is the only difference
- 1Switched from sema at 0.25mg to tirz at 15mg. Different drugs, cannot…4 comments in this branch · started by u/amara_halonen