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Single comment threadYou are looking at one branch of [Discussion] can we stop arguing about tirzepatide until somebody posts a number — 31 comments in the full submission. View in context.
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c/tirzepatide·submitted 1 months ago by u/kaia_wojcik

[Discussion] can we stop arguing about tirzepatide until somebody posts a number

Discussionbranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: tirzepatide matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 4 months without either producing anything. What would actually settle it is 3 people measuring the same…

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6 comments, started 1 months ago
u/certified_referenceQC39 points·1 months ago

week 88 on Mounjaro and the appetite profile is genuinely different from sema

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u/sten_palacios57 points·1 months ago

the nausea from tirz is different, not necessarily worse

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u/certified_referenceQC15 points·1 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/quiet_moderatormod7 points·1 months ago

the 15mg is the top of the pen, not the required dose

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u/tarek_lokken6 points·1 months ago

dual agonism is Mounjaro, do not generalise from semaglutide

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u/kaia_wojcik26 points·1 months ago

Week 63 on Mounjaro and 34kg down. The appetite reduction feels different from sema in ways I do not have words for yet.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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