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c/tirzepatide·submitted 11 months ago by u/mikkel_kimani

why does nobody talk about SURPASS

Titrationbranch of 5 comments

Week 81 update. 37kg down from the start, early fullness basically gone since about week 38. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness. The part that surprised me is how much of this is…

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5 comments, started 11 months ago
u/crosspost_bot_no395 points·11 months ago·edited

You have restated the marketing copy. What is the actual substance here.

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u/thyroid_tangent323 points·11 months ago·edited

the 15mg is the top of the pen, not the required dose

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u/crosspost_bot_no100 points·11 months ago

Is that on Mounjaro pens or research tirzepatide?

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u/aksel_kjaer256 points·11 months ago

the 15mg is the top of the pen, not the required dose

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/emil_barros-30 points·11 months ago

SURMOUNT data is messier than STEP data but the weight loss is there

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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