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c/tirzepatide·posted 1 months ago by u/search_before_post

is it normal to get sulphur burps at week 60

Side Effects Well Actually ×6 Slow Clap ×1

Quick one. Canada here.

15mg works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 23 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

3,922 up / 1,360 down74% upvoted22 commentsid q2gopr16 Jun 2026

22 comments

14 in this archive, depth 4

best — the order this archive was captured in

u/cormac_pereira327 points·1 months ago

Not convinced. The evidence does not support that reading.

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u/aurel_lindqvist202 points·1 months ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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u/certified_referenceQC153 points·1 months ago

Not convinced. The evidence does not support that reading.

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u/santiago_villalobos181 points·1 months ago

SURMOUNT data is messier than STEP data but the weight loss is there

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u/alcohol_aversion90 points·1 months ago
source?
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u/ahmed_iyer55 points·1 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/nabila_ogunleye43 points·1 months ago

Mechanistically the bit that matters is GIP. It explains most of the early profile and a decent chunk of the outcome.

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u/emil_wojcik49 points·1 months ago

the 15mg is the top of the pen, not the required dose

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u/bastian_ekstrom17 points·1 months ago

You have restated the marketing copy. What is the actual substance here.

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u/search_before_postOP-14 points·1 months ago

The dual agonism story is real. The appetite is physically different from semaglutide alone.

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u/ingrid_correia1 point·1 months ago·edited

Did you stay on semaglutide or switch? The outcome is different if you are comparing.

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u/bastian_eriksen22 points·1 months ago

the 15mg is the top of the pen, not the required dose

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u/spain_receta8 points·1 months ago

the 15mg is the top of the pen, not the required dose

Adding to this: dual agonist is doing more work than the comment implies.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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