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c/tirzepatide·submitted 10 months ago by u/quiet_moderator

switched from 12.5mg to 10mg and the nausea got better, not worse

Side Effectsbranch of 6 comments

I have had 12 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 34 days on nominally the same lane, which matters more in summer than in February. The independent number came back 93.7% against a claimed…

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6 comments, started 10 months ago
u/emil_barros622 points·10 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/quiet_moderatorOPmod352 points·10 months ago

stalled on sema, tried tirz, and the curves were actually different shapes

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u/gustav_vermeulen89 points·10 months ago

I am going to push back on this slightly.

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u/vito_chowdhury48 points·10 months ago

the GIP side does different things than the GLP-1 side, that is the point

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u/amara_halonen38 points·10 months ago

the GIP side does different things than the GLP-1 side, that is the point

Yes, exactly this, and it is the bit that took me 67 weeks to accept.

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u/kofi_balogun33 points·10 months ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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