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c/tirzepatide·posted 1 months ago by u/tove_vasquez

[Question] how do you actually verify Mounjaro

Question

Confession thread, sort of.

I went from 0.25mg to 10mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have constipation I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 93 reads it before doing the same thing.

130 up / 5 down96% upvoted20 commentsid qmfw3p22 Jun 2026

20 comments

13 in this archive, depth 4

best — the order this archive was captured in

u/sanne_novak16 points·1 months ago
good post. terrible flair.
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u/quiet_moderatorMOD9 points·1 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/tove_vasquezOP0 points·1 months ago

stalled on sema, tried tirz, and the curves were actually different shapes

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u/nordic_pricing1 point·1 months ago·edited

the reflux from tirz is different, not necessarily worse

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u/copay_card_cc1 point·1 months ago

Not to be pedantic but SURMOUNT and dual agonist are being used interchangeably and they are not interchangeable in real life.

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u/bastian_eriksen11 points·1 months ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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u/signe_villalobos4 points·1 months ago

How long at each step before you escalated?

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u/nabila_ogunleye2 points·1 months ago

the dual agonism hits different and that is why people describe it differently

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u/ahmed_iyer1 point·1 months ago

Hard agree. The food noise disappears differently on the two compounds.

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u/forest_plot_fionastats7 points·1 months ago

Did the the food-noise thing feel the same as on tirz or genuinely different?

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u/mikkel_kimani5 points·1 months ago

Crossposting this to c/coa because the people who need it are not reading this community.

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u/ewan_marchand6 points·1 months ago

dual agonism is Mounjaro, do not generalise from semaglutide

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u/laila_yilmaz3 points·1 months ago·edited

Hard agree. The food noise disappears differently on the two compounds.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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