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c/trialwatch·submitted 2 years ago by u/hugo_norgaard

is it normal to get reflux at week 20

Statsbranch of 10 comments

Quick one. Canada here. endpoint works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 9 weeks and cost roughly what I expected. The admin was worse than the…

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10 comments, started 2 years ago
u/gastric_emptying_g269 points·2 years ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/milan_mensah216 points·2 years ago

Yeah, absolute numbers matter more than the press release.

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u/enzo_ferrari75 points·2 years ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/hugo_bergstrom89 points·2 years ago

Strongly agree. Phase 2 is investigational, not conclusive.

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u/week_one_wanda135 points·2 years ago

absolute risk reduction, not relative risk reduction, that is how you decide

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u/hugo_norgaardOP126 points·2 years ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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u/zaid_roos205 points·2 years ago

dropout handling matters, especially on GI-heavy populations

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u/bastian_ekstrom48 points·2 years ago

This is correct. Discontinuation arms show the regain reality.

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u/iman_castellanos154 points·2 years ago

number-needed-to-treat is the house dialect

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u/week_four_wall226 points·2 years ago

Respectfully this is a sample of one presented as a finding.

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