[Meta] the FLOW rule is doing its job and people should stop complaining
STEP. That is the whole post, but I will justify it.
Everything else people worry about in c/orforglipron is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort STEP out first, and almost nobody does.
I say this having got it wrong for 16 months. My triglycerides was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.
best — the order this archive was captured in
Crossposting this to c/compounding because the people who need it are not reading this community.
Flair changed to match the content. Read the sidebar before posting next time and we are square.
Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.
Flair changed to match the content.
Disagree on that part. 99.0% and 98.9% on the same vial is normal.
Slight fix: the number was 97.6, not 98.9. Decimal point, but a fairly consequential one.
Crossposting this to c/compounding because the people who need it are not reading this community.
Disagree on that part. 98.7% and 98.3% on the same vial is normal.
Crossposting this to c/compounding because the people who need it are not reading this community.
Disagree on that part. 98.1% and 97.6% on the same vial is normal.
absolute risk reduction, not relative risk reduction, that is how you decide
This is the "correlation is mechanism" thing again. You changed three variables at once.
the relative risk reduction in headlines is not the whole story
Crossposting this to c/coa because the people who need it are not reading this community.
- 1Crossposting this to c/compounding because the people who need it are not…7 comments in this branch · started by u/hsa_math