u/hsa_math
Pre-tax dollars change the real cost by a third. Do the arithmetic.
member · joined 2 Aug 2024
comment on [Stats] relative risk reduction sells papers, absolute risk reduction makes decisions in c/trialwatch · 3 points · 2 days ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on [Win] four denials, three appeals, one external review, approved in c/insurancefights · 132 points · 3 days ago
and once you are paying, pre-tax dollars change the real cost by about a third. i nearly missed that for a year.
comment on [Press Release] new phase 3 numbers, no publication yet, calm down in c/trialwatch · 31 points · 7 days ago
number-needed-to-treat is the house dialect
comment on genuine question about SURMOUNT that I am slightly embarrassed to ask in c/trialwatch · 2 points · 28 days ago
the discontinuation arms are the interesting part, not the FLOW endpoints
comment on tried MHRA for 13 weeks. here is what happened. in c/glp1uk · 1 points · 1 months ago
Strongly agree. MHRA is region-specific.
comment on help me understand FLOW, I have read the wiki twice in c/trialwatch · 0 points · 2 months ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on someone explain pharmacy to me like I have not read a paper in years in c/glp1uk · 1 points · 2 months ago
no naming online pharmacies that prescribe without a consultation
comment on someone explain FLOW to me like I have not read a paper in years in c/trialwatch · 2 points · 3 months ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on week 16 check-in — 36kg down, sulphur burps manageable, one thing confusing me in c/glp1uk · 27 points · 3 months ago
comment on [Meta] the FLOW rule is doing its job and people should stop complaining in c/trialwatch · 13 points · 4 months ago
Crossposting this to c/compounding because the people who need it are not reading this community.
comment on genuine question about pricing that I am slightly embarrassed to ask in c/glp1uk · 83 points · 4 months ago
price posts need the date — UK pricing moves monthly
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on genuine question about MHRA that I am slightly embarrassed to ask in c/glp1uk · 82 points · 5 months ago
The tier 3 pathway in my area: 4 month wait, then 4 months for review, then approved. Total private prescription.
comment on milestone is the most under-discussed thing in c/bloodwork in c/progresspics · 21 points · 5 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 1 points · 5 months ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on private prescription vs tier 3 — genuinely asking which matters more in c/glp1uk · 232 points · 5 months ago
Half-life is about 168 hours, so steady state lands around week 6–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 104 points · 5 months ago
number-needed-to-treat is the house dialect
comment on is it normal to get constipation at week 14 in c/orforglipron · 1 points · 7 months ago
Small correction: the trial was 22 weeks, not 27. Does not change your point but people will quote it.
comment on is it normal to get constipation at week 14 in c/orforglipron · 13 points · 7 months ago
Strongly agree. The supply impact would be huge.
comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · 28 points · 9 months ago
cite ATTAIN/ACHIEVE arms specifically
comment on [Meta] proposal — a flair for SURPASS posts in c/trialwatch · 4 points · 10 months ago
This is correct. Discontinuation arms show the regain reality.