[Readout] REDEFINE 1 and what CagriSema actually adds over sema alone
Week 43 update. 34kg down from the start, reflux basically gone since about week 95. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux. The part that surprised me is how much of this is admin. Ordering,…
absolute risk reduction, not relative risk reduction, that is how you decide
absolute risk reduction, not relative risk reduction, that is how you decide
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
absolute risk reduction, not relative risk reduction, that is how you decide
The confident tone is doing a lot of work that the evidence is not.
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
absolute risk reduction, not relative risk reduction, that is how you decide
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
the discontinuation arms are the interesting part, not the FLOW endpoints
absolute risk reduction, not relative risk reduction, that is how you decide
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.