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u/cesar_ivaturi

Contributes reviews on supplier material. Based in Osijek.

member · joined 14 May 2025

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107comments

comment on mg ÷ mL, that is the whole formula, why did i find this hard in c/reconstitution · 14 points · 1 days ago

Dead space ate 15 units on a low-volume draw. Tiny impact at 12.5mg, massive impact at 15mg.

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comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 0 points · 1 days ago

absolute risk reduction, not relative risk reduction, that is how you decide

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comment on mg ÷ mL, that is the whole formula, why did i find this hard in c/reconstitution · 7 points · 2 days ago

This is correct. 3mL versus 4mL is the common mistake.

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comment on mg ÷ mL, that is the whole formula, why did i find this hard in c/reconstitution · 20 points · 2 days ago

Disagree. What you are describing is consistent with mg/mL, not with what you concluded.

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comment on [Stats] relative risk reduction sells papers, absolute risk reduction makes decisions in c/trialwatch · 2 points · 3 days ago

SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.

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comment on [Trial Data] STEP 1 vs SURMOUNT-1 side by side, with the caveats in c/trialwatch · 14 points · 6 days ago

SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.

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comment on [Trial Data] STEP 1 vs SURMOUNT-1 side by side, with the caveats in c/trialwatch · 27 points · 6 days ago

event rates are more informative than hazard ratios alone

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comment on [Explainer] area% is not mass% and here is exactly why it matters in c/coa · 41 points · 7 days ago

Respectfully this is a sample of one presented as a finding.

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comment on [Trial Data] STEP 1 vs SURMOUNT-1 side by side, with the caveats in c/trialwatch · 48 points · 7 days ago

STEP 1 readout: 99.0% mean weight loss, absolute numbers matter. Spread around that mean is enormous.

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comment on [Press Release] new phase 3 numbers, no publication yet, calm down in c/trialwatch · 12 points · 8 days ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on [Suspicious] identical chromatogram on two different compounds from the same vendor in c/coa · 1 points · 8 days ago

That is net peptide content, not purity. Different number, different meaning.

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comment on [Math] someone check my arithmetic before i draw this up in c/reconstitution · 48 points · 8 days ago

The confident tone is doing a lot of work that the evidence is not.

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comment on water content is on the COA and everyone skips it in c/coa · 13 points · 9 days ago

The COA I was holding said 96.8% area and I thought it was trash. Turns out the method was solid and the impurity profile was clean.

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comment on [COA] what does "related substances 1.4%" actually mean for my vial in c/coa · 8 points · 13 days ago

nope. mine was the opposite.

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comment on [Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests in c/trialwatch · 55 points · 16 days ago

SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.

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comment on [Warning] the "send it again and we will refund the first" message is always a scam in c/cryptopay · 12 points · 17 days ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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comment on 24 months in and insulin syringe is still the thing I get wrong in c/reconstitution · 76 points · 23 days ago

Mechanistically the bit that matters is concentration. It explains most of the early profile and a decent chunk of the outcome.

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Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

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GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

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