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u/curious_panel_only

Came for one answer, stayed for three years.

long-standing contributor · joined 17 Jun 2023

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139comments

Comments — page 5 of 5

comment on [Question] Mounjaro — what am I missing here in c/tirzepatide · 49 points · 1 year ago

Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.

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comment on [PSA] escrow is not what most of this community thinks it is in c/cryptopay · 14 points · 1 year ago

Which network and did the vendor confirm they credit it?

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comment on [PSA] escrow is not what most of this community thinks it is in c/cryptopay · 181 points · 1 year ago

the 4% discount versus 39% network fees

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comment on [Question] Australia — has anyone got a straight answer on what is in c/newbiequestions · 32 points · 1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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comment on stability — my 18-week log, condensed into one table in c/coldchain · 23 points · 1 year ago

Spain to Spain: 16 days with CPC and 13 days with FGP. Same route, different carriers, variance is real.

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comment on what would you tell week-1 you about hazard ratio in c/trialwatch · 6 points · 1 year ago

number-needed-to-treat is the house dialect

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comment on SELECT — 9 things I got wrong before I got it right in c/trialwatch · -27 points · 1 year ago

Yeah, absolute numbers matter more than the press release.

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comment on Germany: SURMOUNT, and what it actually costs here in c/tirzepatide · 1 points · 1 year ago

Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.

Yes, exactly this, and it is the bit that took me 76 weeks to accept.

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comment on [Lab] 4th independent test on BCH, and the trend is the interesting part in c/trialwatch · 28 points · 1 year ago

SELECT reported a SURMOUNT hazard ratio but the absolute event rate is what changes clinical practice.

Yes, exactly this, and it is the bit that took me 2 weeks to accept.

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comment on [Discussion] can we stop arguing about Zepbound until somebody posts a number in c/tirzepatide · 125 points · 1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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comment on what would you tell week-1 you about data logger in c/coldchain · 44 points · 1 year ago

lane reports need origin, destination, carrier, and actual transit days

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comment on what is is the most under-discussed thing in c/meta in c/newbiequestions · 82 points · 1 year ago

Yeah, that is totally normal for week 9.

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comment on [Discussion] we are measuring packaging at the wrong time and calling it noise in c/coldchain · 0 points · 1 year ago

This is correct. Dry powder is way more robust than liquid.

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comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 41 points · 1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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comment on [Meta] the pricing rule is doing its job and people should stop complaining in c/glp1uk · 23 points · 1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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comment on [Meta] the pricing rule is doing its job and people should stop complaining in c/glp1uk · 11 points · 1 year ago

That is net peptide content, not purity. Different number, different meaning.

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comment on does BPC-157 actually matter or is it forum lore at this point in c/bpc157 · 4 points · 1 year ago

Slight fix: the number was 96.8, not 98.0. Decimal point, but a fairly consequential one.

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comment on [Vendor] WXT order #2 — France, 33 days, no drama, receipts inside in c/tirzepatide · 8 points · 1 year ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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comment on [Vendor] WXT order #2 — France, 33 days, no drama, receipts inside in c/tirzepatide · 49 points · 1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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comment on someone explain pricing to me like I have not read a paper in years in c/glp1uk · 472 points · 1 year ago

Small correction: the trial was 15 weeks, not 31. Does not change your point but people will quote it.

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