u/dario_stanescu

Half-life is about 168 hours, so steady state lands around week 7–5.

Yes, exactly this, and it is the bit that took me 64 weeks to accept.

appetite return timelines vary interval stretching

This is correct. The shortage list does expire and the rules change.

telehealth costs 503B plus compounding markup, total varies

Yeah, 503A and 503B are different regulatory animals.

rapid loss plus no protein equals muscle loss

private 0.25mg is UK in Spain this month

the nausea from tirz is different, not necessarily worse

cite the discontinuation data rather than guessing regain rates

the dual agonism hits different and that is why people describe it differently

You have restated the marketing copy. What is the actual substance here.

the regain is treatment of chronic condition ending, not failure

Hard agree. The food noise disappears differently on the two compounds.

Slight fix: the number was 96.8, not 94.2. Decimal point, but a fairly consequential one.

Is that on Mounjaro pens or research tirzepatide?

stalled on sema, tried tirz, and the curves were actually different shapes

Which country? Half the answers in this thread only apply in Denmark.

price posts need the date — UK pricing moves monthly

SURMOUNT data is messier than STEP data but the weight loss is there

This is correct. The shortage list does expire and the rules change.