Long-ish post, sorry. tl;dr at the bottom. I have been tracking orforglipron against ApoB for 7 weeks because I could not find anyone who had. The correlation is weaker…
u/freya_marchand
Contributes reviews on supplier material. Based in Cork.
member · joined 15 Jun 2025
comment on [Trial Data] ATTAIN-1 numbers, and why the % is not the headline in c/orforglipron · -15 points · 3 days ago
no cold chain means ATTAIN, if approved
comment on [Meta] the small molecule rule is doing its job and people should stop complaining in c/orforglipron · 17 points · 2 months ago
The muscle cramps was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.
Week 2 update. 13kg down from the start, muscle cramps basically gone since about week 54. Things that worked: consistency, protein at breakfast, walking more than I…
comment on my hs-CRP moved and I cannot work out whether small molecule is why in c/orforglipron · 1 points · 9 months ago
oral non-peptide agonist is ACHIEVE, no food restrictions
comment on [Question] how do you actually verify oral GLP-1 in c/orforglipron · 10 points · 10 months ago
Which country? Half the answers in this thread only apply in Canada.
comment on [Discussion] the small molecule advice in here is 19 years out of date in c/orforglipron · 4 points · 11 months ago
small molecule, not a peptide, purity discussion is different
comment on orforglipron vs ATTAIN — genuinely asking which matters more in c/orforglipron · 87 points · 1 year ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Discussion] the ACHIEVE advice in here is 11 years out of date in c/orforglipron · 3 points · 1 year ago
oral non-peptide agonist is ACHIEVE, no food restrictions
comment on genuine question about ATTAIN that I am slightly embarrassed to ask in c/orforglipron · 2 points · 1 year ago
ATTAIN and ACHIEVE are phase 16 trials
comment on 20 months in and non-peptide is still the thing I get wrong in c/orforglipron · -11 points · 2 years ago