[Discussion] the ACHIEVE advice in here is 11 years out of date
Posting this because I searched for it and got nothing useful.
Setup: 15mg, week 60, constipation present but not ruining anything. I changed exactly one variable — ATTAIN — and tracked it for 14 weeks.
Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.
Not medical advice, obviously. This is one person with a spreadsheet.
best — the order this archive was captured in
Yeah, small molecule changes the whole game.
Came off after 89 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.
This is the "correlation is mechanism" thing again. You changed three variables at once.
Yeah, small molecule changes the whole game.
Stalled for 24 weeks, changed nothing, and it started moving again on week 86.
Disagree. What you are describing is consistent with ACHIEVE, not with what you concluded.
Disagree.
Adding to this: non-peptide is doing more work than the comment implies.
small molecule purity is different testing than peptides
the small molecule is whether this actually works long-term
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
Retitled to remove editorialising. Put the evidence in the body.
The confident tone is doing a lot of work that the evidence is not.
the nausea profile is speculative at this stage
Not to be pedantic but oral GLP-1 and small molecule are being used interchangeably and they are not interchangeable in real life.
Not to be pedantic but oral GLP-1 and small molecule are being used interchangeably and they are not interchangeable in real life.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
the reflux profile is speculative at this stage
the absorption problem is solved by non-peptide structure
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
oral non-peptide agonist is ACHIEVE, no food restrictions
- 1Retitled to remove editorialising. Put the evidence in the body.7 comments in this branch · started by u/phase_two_pete
- 2Yeah, small molecule changes the whole game.6 comments in this branch · started by u/laila_delgado