my hs-CRP moved and I cannot work out whether small molecule is why
Confession thread, sort of.
I went from 15mg to 7.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 3 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have early fullness I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 15 reads it before doing the same thing.
best — the order this archive was captured in
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
Yeah, small molecule changes the whole game.
This is the "correlation is mechanism" thing again. You changed three variables at once.
phase 22 data is interesting, phase 38 will tell the real story
the small molecule is whether this actually works long-term
Every time this gets posted it hits the front page and every time someone has to re-explain it.
Yeah, small molecule changes the whole game.
[deleted]
the fatigue profile is speculative at this stage
The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.
Respectfully this is a sample of one presented as a finding.
Disagree but this is the good kind of wrong — it is specific enough to be checked.
The thing nobody prepared me for was the quiet.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
the absorption problem is solved by non-peptide structure
Genuine question — what concentration were you at?
the small molecule is whether this actually works long-term
Maintenance for 3 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.
oral non-peptide agonist is ACHIEVE, no food restrictions
- 1The thing nobody prepared me for was the quiet. Not the appetite, the quiet…5 comments in this branch · started by u/emil_marchand
- 2Every time this gets posted it hits the front page and every time someone…4 comments in this branch · started by u/hedda_ekstrom