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u/honest_syringe_2025

Not a chemist. Increasingly acting like one.

newer member · joined 7 Apr 2025

21,596post karma
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103comments

Comments — page 3 of 5

comment on what changed for me between week 20 and week 63 in c/compounding · 42 points · 6 months ago

The telehealth + compounding combo cost telehealth plus 23% markup. Not cheap but covered by insurance depending on state.

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comment on [PSA] tapering is not what most of this community thinks it is in c/tapering · 92 points · 6 months ago

This is correct. Discontinuation data is real.

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comment on [PSA] tapering is not what most of this community thinks it is in c/tapering · 107 points · 6 months ago

appetite return timelines vary interval stretching

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comment on 4 months in and dead space is still the thing I get wrong in c/reconstitution · 86 points · 6 months ago

This is correct. 2mL versus 21mL is the common mistake.

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comment on 4 months in and dead space is still the thing I get wrong in c/reconstitution · 287 points · 6 months ago

Small correction: the trial was 13 weeks, not 35.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on 4 months in and dead space is still the thing I get wrong in c/reconstitution · 544 points · 6 months ago

Small correction: the trial was 13 weeks, not 35. Does not change your point but people will quote it.

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comment on reading retatrutide threads from 2024 and half of it aged badly in c/retatrutide · 455 points · 7 months ago

Respectfully this is a sample of one presented as a finding.

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comment on [Question] 503B — what am I missing here in c/compounding · 13 points · 7 months ago

regulatory claims need a citation to the actual rule, not interpretation

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comment on [Question] 503B — what am I missing here in c/compounding · 19 points · 7 months ago

telehealth prescriber models exist, pricing differs by state

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comment on [Question] New Zealand — has anyone got a straight answer on LC-MS in c/hplc · 64 points · 7 months ago

This is the correct method framing. Column and gradient are load-bearing fields.

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comment on [Meta] proposal — a flair for 503B posts in c/compounding · 10 points · 8 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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comment on the Netherlands: dead space, and what it actually costs here in c/reconstitution · 128 points · 8 months ago

This is correct. 3mL versus 15mL is the common mistake.

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comment on is it normal to get nausea at week 19 in c/reconstitution · 7 points · 8 months ago

Small correction: the trial was 11 weeks, not 3. Does not change your point but people will quote it.

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comment on retatrutide vs triple agonist — genuinely asking which matters more in c/retatrutide · 310 points · 8 months ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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comment on is it normal to get constipation at week 95 in c/reconstitution · -20 points · 8 months ago

This is correct. 2mL versus 3mL is the common mistake.

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comment on 15 months in and purity is still the thing I get wrong in c/hplc · 0 points · 9 months ago

area% and mass% are not the same and this whole post conflates them

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comment on three years of LC-MS threads, summarised so you do not have to read them in c/hplc · 1 points · 9 months ago

This is the correct method framing. Column and gradient are load-bearing fields.

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comment on the TRIUMPH thing finally clicked for me and I want to write it down in c/retatrutide · 1 points · 10 months ago

phase 2 numbers are not maintenance numbers, cite the trial

Adding to this: triple agonist is doing more work than the comment implies.

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comment on 14 months in and insulin resistance is still the thing I get wrong in c/glp1women · 5 points · 10 months ago

perimenopause and menopause weight physiology

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comment on LC-MS: the version I wish someone had shown me in week 1 in c/hplc · 241 points · 10 months ago

Detection wavelength? method development and that changes at different wavelengths.

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