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c/compounding·posted 6 months ago by u/medutest_mel

what changed for me between week 20 and week 63

Question Long Haul ×8 Sourced ×3

Something I noticed reading old threads that I have not seen said out loud.

The advice on 503B in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

2,248 up / 234 down91% upvoted57 commentsid o6ue6l24 Jan 2026

57 comments

27 in this archive, depth 5

best — the order this archive was captured in

u/neha_krastev424 points·6 months ago·edited

503B compounding is different from 503A, different rules, different legality

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u/prior_auth_painMOD253 points·6 months ago·edited

Removed a chain here. The rule is one line long and it is not negotiable.

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u/food_noise_gonemaintenance159 points·6 months ago

shortage list status is telehealth, check the actual list

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u/burned_once_twice181 points·6 months ago

Respectfully this is a sample of one presented as a finding.

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[removed]117 points·6 months ago

[removed by moderator]

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u/formulary_fighterappeals-1 point·6 months ago

the the UK situation is different from the US, different regulations

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u/ireland_drugs_pay254 points·6 months ago

Respectfully this is a sample of one presented as a finding.

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u/priya_palacios138 points·6 months ago·edited

Moved states and the compounding landscape changed completely. Different rules, different pharmacies, different costs.

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u/medutest_melOP114 points·6 months ago

The 503A pharmacy I used lost their shortage list eligibility. Same day, compounding became illegal. Rules are real.

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u/rt_shift_reggie80 points·6 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/elin_ferrari46 points·6 months ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/enzo_ferrari18 points·6 months ago

The confident tone is doing a lot of work that the evidence is not.

Disagree on that part. 99.2% and 99.3% on the same vial is normal.

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u/bilal_osei94 points·6 months ago

Not convinced. The evidence does not support that reading.

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u/bruno_dumitru39 points·6 months ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/hugo_bergstrom60 points·6 months ago

Crossposting this to c/t2dglp1 because the people who need it are not reading this community.

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u/burned_once_twice18 points·6 months ago

regulatory claims need a citation to the actual rule, not interpretation

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u/emil_okwuosa32 points·6 months ago

What is the actual shortage list status right now?

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u/medutest_melOP25 points·6 months ago

API transparency is the question that separates good compounders from sketchy ones

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u/clara_danquah8 points·6 months ago

Strongly agree. API source transparency matters.

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u/escrow_evangelist6 points·6 months ago

telehealth costs 503B plus compounding markup, total varies

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u/hugo_bergstrom4 points·6 months ago

telehealth costs 503B plus compounding markup, total varies

Yes, exactly this, and it is the bit that took me 4 weeks to accept.

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u/step_therapy_s39 points·6 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/honest_syringe_202542 points·6 months ago

The telehealth + compounding combo cost telehealth plus 23% markup. Not cheap but covered by insurance depending on state.

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u/joaquin_trevino19 points·6 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/medutest_melOP8 points·6 months ago

API source questions are on-topic and compounders dodging them is newsworthy

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u/formulary_fighterappeals9 points·6 months ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/kian_ferreira26 points·6 months ago

telehealth costs 503A plus compounding markup, total varies

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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c/compounding rules
  1. Regulatory claims need a citation to the actual rule, notice or docket.
  2. No pharmacy referral codes. Naming a pharmacy is fine; recruiting for it is not.
  3. API source questions are on-topic and pharmacies dodging them is newsworthy.
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