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Overview — page 5 of 5

comment on three years of biopsy threads, summarised so you do not have to read them in c/survodutide · 3 points · 1 year ago

phase 18 data is interesting, phase 34 will be different

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comment on am I the only one who found GIP harder than the injections in c/tirzepatide · 439 points · 1 year ago

The SURMOUNT readouts are real but less consistent than STEP.

Yes, exactly this, and it is the bit that took me 60 weeks to accept.

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comment on CagriSema vs REDEFINE — genuinely asking which matters more in c/cagrilintide · 1 points · 1 year ago

Yeah, amylin is doing different work than GLP-1.

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comment on CagriSema vs REDEFINE — genuinely asking which matters more in c/cagrilintide · 24 points · 1 year ago

the mechanism is different, the side effect profile reflects it

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comment on [Vendor] WXT order #20 — France, 9 days, no drama, receipts inside in c/trialwatch · 199 points · 1 year ago

Yeah, absolute numbers matter more than the press release.

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comment on meta — my 21-week log, condensed into one table in c/meta · 1 points · 1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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comment on [Discussion] the endpoint advice in here is 5 years out of date in c/trialwatch · 8 points · 1 year ago

phase 2 is not phase 3, smaller n and shorter trial

Yes, exactly this, and it is the bit that took me 75 weeks to accept.

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comment on [Vendor] WXT order #23 — France, 9 days, no drama, receipts inside in c/trialwatch · 199 points · 1 year ago

dropout handling matters, especially on GI-heavy populations

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comment on anyone else notice moderation kicking in around week 4 in c/meta · 121 points · 1 year ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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comment on anyone else notice moderation kicking in around week 4 in c/meta · 44 points · 1 year ago

Maintenance for 17 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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comment on week 96 check-in — 11kg down, the food-noise thing manageable, one thing confusing me in c/tirzepatide · 11 points · 1 year ago

the early fullness from tirz is different, not necessarily worse

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comment on [Discussion] the regain advice in here is 21 years out of date in c/maintenancephase · 104 points · 1 year ago

The plateau is real and boring. 74 weeks at the same weight, then movement again. Patience was the intervention.

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comment on [Question] how do you actually verify units in c/reconstitution · 1.1k points · 1 year ago

this deserves more than 18 upvotes

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comment on [Discussion] we are measuring bacteriostatic water at the wrong time and calling it noise in c/reconstitution · 36 points · 1 year ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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comment on [Question] how do you actually verify disclosure in c/meta · 173 points · 1 year ago

Retitled to remove editorialising. Put the evidence in the body.

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comment on week 71 check-in — 17kg down, fatigue manageable, one thing confusing me in c/tirzepatide · 0 points · 1 year ago

Small correction: the trial was 24 weeks, not 39. Does not change your point but people will quote it.

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comment on lowest effective dose is the most under-discussed thing in c/trialwatch in c/maintenancephase · -34 points · 1 year ago

the maintenance question changes at maintenance

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comment on unpopular opinion: regain is massively overrated in c/maintenancephase · 1 points · 1 year ago

the long term question changes at maintenance

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comment on tried tirzepatide for 24 weeks. here is what happened. in c/tirzepatide · 403 points · 1 year ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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comment on goal weight — 16 things I got wrong before I got it right in c/maintenancephase · 20 points · 1 year ago

Respectfully this is a sample of one presented as a finding.

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