[Vendor] WXT order #20 — France, 9 days, no drama, receipts inside
Quick one. Canada here.
endpoint works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.
Specifics: the route I used took 18 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.
Happy to answer questions from anyone in the same jurisdiction.
best — the order this archive was captured in
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
number-needed-to-treat is the house dialect
Yeah, absolute numbers matter more than the press release.
STEP 1 readout: 98.9% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
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Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
phase 2 is not phase 3, smaller n and shorter trial
phase 2 is not phase 3, smaller n and shorter trial
Disagree on that part. 98.1% and 99.3% on the same vial is normal.
event rates are more informative than hazard ratios alone
dropout handling matters, especially on GI-heavy populations
dropout handling matters, especially on GI-heavy populations
Yes, exactly this, and it is the bit that took me 96 weeks to accept.
press release TRIUMPH posts must be flaired until a publication exists
phase 2 is not phase 3, smaller n and shorter trial
absolute risk reduction, not relative risk reduction, that is how you decide
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
give the trial name, phase, n, and primary endpoint in the body
Which trial and what was the primary endpoint?
This is correct. Discontinuation arms show the regain reality.
Tracking number removed. It identifies both ends of a shipment.
Titration speed is a side-effect dial far more than an efficacy dial.
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
Strongly agree. Phase 2 is investigational, not conclusive.
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
- 1press release TRIUMPH posts must be flaired until a publication exists9 comments in this branch · started by u/hamza_zielinski
- 2Three years on this site and the questions have not changed at all. Which is…5 comments in this branch · started by u/alcohol_aversion